Cytopathic effects in cells in the brain and infected T cells may develop immune deficiencies and neurological diseases induced by HIV and related lentiviruses. Retrovirus causes immunological diseases including HIV and T-Cell leukaemia. Acquired immune deficiency syndrome (AIDS) caused by retrovirus known as human immunodeficiency virus (HIV) and T-Cell leukaemia caused by human T lymphotropic virus (HTLV). Antiretroviral medicine are the medicine that acts or inhibit certain process in viral replication and inhibits further worsening of the diseases.
Globally antiretroviral medicine market driven by increased cases of retroviral infections such as especially HIV/AIDS. According to WHO, 36.7 million people were diagnosed with HIV/AIDS in 2015, whereas, 1.1 million people died of AIDS related illness in the same year. The higher prevalence of HIV owing to the various factors such as lack of availability of medicine for the treatment of HIV infection, promising pipeline medicine, increased funding by the government are expected to bolster the antiretroviral medicine market over the forecast period. However, high costs of R&D and stringent regulatory procedures hampering the antiretroviral medicine market. Furthermore, availability of the generic versions of blockbuster medicine affecting the market revenue of antiretroviral medicine.
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Global antiretroviral medicine market is segmented based on drug class, route of administration, and distribution channel
Based on drug class, antiretroviral medicine are classified into
Nucleoside Reverse Transcriptase Inhibitors (NRT’s)
Non- Nucleoside Reverse Transcriptase Inhibitors (NNRT’s)
Protease Inhibitors
Integrate Inhibitors
Fusion Inhibitors
Chemokine Receptor Inhibitors
Others
Based on route of administration, antiretroviral medicine are classified into
Oral
Parenteral
Based on distribution channel, antiretroviral medicine market is classified into
Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
Others
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Antiretroviral medicine market is expected to grow at significant rates during forecasting period owing to pipeline medicine such as doravirine (Merck & Co.), fostemsavir (Bristol-Myers Squibb), rilpivirine (Tibotec) etc. Market players are adopting strategies like mergers and acquisitions to improve the market share. In December 2015, ViiV Healthcare purchased Bristol-Myers Squibb’s late stage HIV R&D assets.
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Some of the players in the antiretroviral medicine market are Abbott Laboratories (U.S.), AstraZeneca plc (U.K.), Modified Polymer Components, Inc. (Bristol-Myers-Squibb) (U.S), Gilead Sciences (U.S.), GlaxoSmithKline Plc (U.K.), and F. Hoffmann-La Roche AG (Switzerland) to name a few
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