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Breaking News:

• Avalon and research partner, Massachusetts Institute of Technology (MIT), combine their protein design “QTY Code” technology with Google’s DeepMind artificial intelligence (AI) program, AlphaFold2, to accurately predict the 3D structures of protein receptors that have potential use as cellular therapy targets

• A study of the application and capabilities of the dual technology was published in the November 2021 issue of Life, a peer-reviewed life sciences journal

FREEHOLD, N.J., December, 2021 -- Avalon GloboCare Corp. (NASDAQ: AVCO), a clinical-stage global developer of cell-based technologies and therapeutics, today announced further advancement of the Company’s sponsored research and licensing agreement with the Massachusetts Institute of Technology (MIT). Avalon and MIT have combined their artificial intelligence (AI)-enhanced protein design “QTY Code” technology with Google’s AlphaFold2, a DeepMind AI program developed to predict 3-dimensional (3D) protein structures of previously difficult to work with drug targets. This new system is designed to accelerate and advance Avalon’s capabilities in developing novel targets for immuno-oncology and cellular medicine.

Combining the “QTY code” with AlphaFold2, provides Avalon with a novel, accurate, and efficient in-silico tool to improve knowledge about important potential therapeutic targets such as transmembrane receptors and other proteins to better understand their biology and facilitate the development of novel cellular therapies.

“This new study with our collaborator, Dr. Shuguang Zhang from MIT, has validated the innovative application of the QTY code technology to transform important cellular therapy targets that have been previously difficult to work with in the laboratory,” said David Jin, M.D., Ph.D., President and Chief Executive Officer of Avalon. “This new approach is advancing our capabilities in designing novel immuno-oncology and cellular medicine therapies and we are excited to continue to work with Dr. Zhang to advance these drug development technologies,” added Dr. Jin.

The study of the new dual technology application was published in the November 2021 issue of Life, an international, peer-reviewed, open-access life sciences journal.

The new technology is a direct result of a collaboration between AVCO and researchers at BOKU, Vienna, the University of Vienna, the Science for Life Laboratory within the Division of Nanobiotechnology at the KTH Royal Institute of Technology in Stockholm, Sweden and the Department of Biochemistry at the King Abdulaziz University in Jeddah, Saudi Arabia.

For more information on Avalon GloboCare Corp. (NASDAQ: AVCO) visit:

www.avalon-globocare.com